Bioactivity | PW0729 (compound 15b) is an orphan GPR52 agonist with potential applications in GPR52 activation, signaling bias, and neuropsychiatric and neurological disorders. The brain exposure characteristics of PW0729 need to be further optimized[1]. |
CAS | 2767348-36-5 |
Formula | C23H22F3N3O2 |
Molar Mass | 429.43 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Murphy R E, Wang P, Ali S, et al. Discovery of 3-((4-Benzylpyridin-2-yl) amino) benzamides as Potent GPR52 G Protein-Biased Agonists[J]. Journal of Medicinal Chemistry, 2024. |