| Bioactivity | PTZ-343 is a potent enhancer of Luminol (HY-15922). PTZ-343 greatly increases the light output of the peroxidase-catalyzed luminol chemiluminescent oxidation reaction (>80%)[1][2]. |
| Invitro | PTZ-343 behaves as electron transfer mediator, it reacts with HRP-II to release HRP and a enhance (PTZ-343) radical. The enhancer (PTZ-343) radical quickly oxidizes luminol anions to induce light emission[1]. |
| Name | PTZ-343 |
| CAS | 101199-38-6 |
| Formula | C15H14NNaO3S2 |
| Molar Mass | 343.40 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Ettore Marzocchi, et al. Chemiluminescent detection systems of horseradish peroxidase employing nucleophilic acylation catalysts. Anal Biochem. 2008 Jun 15;377(2):189-94. [2]. WenxiaZhang, et al. A novel electrochemical biomimetic sensor based on E-MIP artificial acceptor and SI-ATRP assisted signal amplification. Journal of Electroanalytical Chemistry. Volume 842, 1 June 2019, Pages 24-33 |