| Bioactivity | PTX80 is an antagonist of p62 with an IC50 value of 31.18 nM. PTX80 reduces tumor volume in an HCT116 colorectal cancer mouse xenograft model[1]. |
| CAS | 2376297-69-5 |
| Formula | C26H26N4O3S |
| Molar Mass | 474.57 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ori Kalid, et al. PTX80, a novel compound targeting the autophagy receptor p62/SQSTM1 for treatment of cancer. Chem Biol Drug Des. 2022 Nov;100(5):623-638. |