PTP1B-IN-22_product_DataBase

CAS: 86109-60-6 F: C16H12N2O3S2 W: 344.41

PTP1B-IN-22, a ZINC02765569 derivative, is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor. PTP1B-IN-22 has P

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Bioactivity	PTP1B-IN-22, a ZINC02765569 derivative, is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor. PTP1B-IN-22 has PTP1B inhibition and glucose uptake in skeletal muscle L6 myotubes[1].
Invitro	PTP1B-IN-22 (compound 3j; 骨骼肌 L6 肌管) 表现出 66.4% 的体外 PTP1B 抑制和 39.6% 的葡萄糖摄取增加[1]。
Name	PTP1B-IN-22
CAS	86109-60-6
Formula	C16H12N2O3S2
Molar Mass	344.41
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reference	[1]. Prashant J, et, al. Molecular modeling and synthesis of ZINC02765569 derivatives as protein tyrosine phosphatase 1B inhibitors: lead optimization study. 2012;22: 1618-23.

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