| Bioactivity | PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA)[1][2]. |
| Name | PSMα3 |
| CAS | 1001405-52-2 |
| Sequence | {f}-Met-Glu-Phe-Val-Ala-Lys-Leu-Phe-Lys-Phe-Phe-Lys-Asp-Leu-Leu-Gly-Lys-Phe-Leu-Gly-Asn-Asn |
| Shortening | {f}-MEFVAKLFKFFKDLLGKFLGNN |
| Formula | C128H192N28O30S |
| Molar Mass | 2635.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
PSMα3
CAS: 1001405-52-2 F: C128H192N28O30S W: 2635.13
PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modu
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