Bioactivity | PSMA-Val-Cit-PAB-Azide is a drug-linker conjugate for ADC. PSMA-Val-Cit-PAB-Azide contains the cleavable ADCs linker (Val-Cit-PAB) and a novel small-molecule PSMA-targeted conjugate. It contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups[1]. |
CAS | 2374814-84-1 |
Formula | C50H65ClN10O13 |
Molar Mass | 1049.56 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Aleksei E Machulkin, et al. Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin E Conjugate. J Med Chem. 2021 Dec 9;64(23):17123-17145. |