PSMA-D5_product_DataBase

Bioactivity	PSMA-D5 has a binding affinity for PSMA with Ki of 0.21 nM and can be used for PSMA tracing after radiolabeling. PSMA-D5 ([68Ga]-labeled) contains a DOTA chelator, allowing convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. PSMA-D5 ([68Ga]-labeled) shows excellent pharmacokinetic properties, exhibiting remarkable tumor uptake in 22Rv1 tumors[1].
Invitro	PSMA-D5 ([68Ga] 标记) (1 h) 在 PSMA 阳性的 22Rv1 细胞中表现出卓越的摄取性能 (摄取值：1.68) [1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PSMA-D5 相关抗体:
In Vivo	PSMA-D5 ([68Ga] 标记) (∼3.7 MBq，静脉注射) 在 22Rv1 肿瘤中显示出高的肿瘤摄取率（SUVmax = 3.51），与 PSMA-11 ([68Ga] 标记) 相比 (T/M 值分别为 32.01 和 26.8)，能更好地显示较小的病灶。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.
CAS	3056440-83-3
Formula	C57H80N12O24
Molar Mass	1317.31
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Chen Y, et al. Synthesis, Preclinical Evaluation, and First-in-Human PET Study of [68Ga]-Labeled Biphenyl-Containing PSMA Tracers. J Med Chem. 2023 Sep 28;66(18):13332-13345.

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