| Bioactivity | PSB-KK1445 is a potent and selective GPR18 agonist with EC50s of 45.4 nM and 124 nM for human and mouse GPR18, respectively. PSB-KK1445 displays >200-fold selectivity versus both CB receptor subtypes, GPR55, and GPR183[1]. |
| Target | EC50: 45.4 nM (Human GPR18) and 124 nM (Mouse GPR18) |
| CAS | 885896-54-8 |
| Formula | C24H23FN6O2 |
| Molar Mass | 446.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Andhika B Mahardhika, et al. Potent, Selective Agonists for the Cannabinoid-like Orphan G Protein-Coupled Receptor GPR18: A Promising Drug Target for Cancer and Immunity. J Med Chem. 2024 Jun 27;67(12):9896-9926. |
PSB-KK1445
CAS: 885896-54-8 F: C24H23FN6O2 W: 446.48
PSB-KK1445 is a potent and selective GPR18 agonist with EC50s of 45.4 nM and 124 nM for human and mouse GPR18, respectiv
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