| Bioactivity | PS-166276 is a highly potent and less cytotoxic inhibitor of p38. PS166276 has an IC50 of 28 nM at p38 kinase and 170 nM in the THP-1 TNFα assay[1]. |
| In Vivo | PS166276 (30 mg/kg, s.c. mice) 在老鼠中抑制 LPS 诱导的 TNFα 产生。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 348089-57-6 |
| Formula | C20H30N8O |
| Molar Mass | 398.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tsung H Lin, et al. Discovery and characterization of triaminotriazine aniline amides as highly selective p38 kinase inhibitors. J Pharmacol Exp Ther. 2006 Aug;318(2):495-502. |
PS-166276
CAS: 348089-57-6 F: C20H30N8O W: 398.51
PS-166276 is a highly potent and less cytotoxic inhibitor of p38. PS166276 has an IC50 of 28 nM at p38 kinase and 170 nM
Data collection：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.