Bioactivity | PROTAC eDHFR Degrader-2 (compound 7b) is a potent degrader targeting Escherichia coli dihydrofolate reductase (eDHFR), enabling robust degradation of eDHFR-tagged proteins[1]. |
Target | eDHFR |
Name | PROTAC eDHFR Degrader-2 |
Formula | C34H40N8O9 |
Molar Mass | 704.73 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Etersque JM et al. Regulation of eDHFR-tagged proteins with trimethoprim PROTACs. Nat Commun. 2023 Nov 3;14(1):7071. |