| Bioactivity | PROTAC c-Met degrader-2 (PROTAC2) is a PROTAC-based c-Met degrader, with a DC50 of 50 nM (Pink: Foretinib (HY-10338); Black: linker (HY-45124); Blue: CRBN ligand Thalidomide-4-O-C2-NH2 (HY-136162A))[1][2]. |
| CAS | 2254608-80-3 |
| Formula | C51H50F2N6O13 |
| Molar Mass | 992.97 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nan Bai, et al. Rationalizing PROTAC-Mediated Ternary Complex Formation Using Rosetta. J Chem Inf Model [2]. Andrew P. Crew, et al. Modulators of proteolysis and associated methods of use. WO2018226542A1. |
PROTAC c-Met degrader-2
CAS: 2254608-80-3 F: C51H50F2N6O13 W: 992.97
PROTAC c-Met degrader-2 (PROTAC2) is a PROTAC-based c-Met degrader, with a DC50 of 50 nM (Pink: Foretinib (HY-10338); Bl
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This product is for research use only, not for human use. We do not sell to patients.