PROTAC TYK2 degradation agent1

CAS: F: C55H69N13O7S W: 1056.28

PROTAC TYK2 degradation agent1 is a potent and subtype-selective TYK2 degrader. PROTAC TYK2 degradation agent1 has TYK2

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Bioactivity	PROTAC TYK2 degradation agent1 is a potent and subtype-selective TYK2 degrader. PROTAC TYK2 degradation agent1 has TYK2 degradation activity with DC50 value of 14 nM. PROTAC TYK2 degradation agent1 can be used for the research of autoimmune disease[1].
Target	DC50: 14 nM (TYK2)
Invitro	PROTAC TYK2 degradation agent1 (degrader 37) (1 µM; 6 h) 选择性抑制 TYK2 蛋白水平[1]。PROTAC TYK2 degradation agent1 具有 TYK2 降解活性，DC50 值为 14 nM[1]。 Western Blot Analysis[1] Cell Line:
Name	PROTAC TYK2 degradation agent1
Formula	C55H69N13O7S
Molar Mass	1056.28
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Jun-Ya Kato, et al. Discovery of a potent and subtype-selective TYK2 degrader based on an allosteric TYK2 inhibitor. Bioorg Med Chem Lett. 2023 Jan 1;79:129083.