Bioactivity | SMARCA2/4-degrader-6 (compound I-438) is a SMARCA2/4 degrader[1]. SMARCA2/4-degrader-6 has the potential for the research of cancer[1]. |
Invitro | SMARCA2/4-degrader-6 (compound I-438) (0-1000 nM; 24 h) 诱导 MV4-11 细胞中的 SMARCA2、SMARCA4 蛋白质降解,对 SMARCA2 和 SMARCA4 的 DC50 值分别为 0 --> PROTAC SMARCA2/4-degrader-6 相关抗体: |
CAS | 2568277-87-0 |
Formula | C50H61N11O5S |
Molar Mass | 928.16 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Nan Ji, et al. Smarca degraders and uses thereof. US20230072658A1. |