PeptideDB

PROTAC SMARCA2/4-degrader-32

CAS: 2568273-79-8 F: C54H69N13O5S W: 1012.27

PROTAC SMARCA2/4-degrader-32 (compound I-446) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity PROTAC SMARCA2/4-degrader-32 (compound I-446) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC50s 90 after 24 h of treatment[1].
Target SMARCA2/4
CAS 2568273-79-8
Formula C54H69N13O5S
Molar Mass 1012.27
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.