| Bioactivity | PROTAC SMARCA2/4-degrader-26 is a PROTAC targeting SMARCA2/4. PROTAC SMARCA2/4-degrader-25 is composed of PROTAC target protein ligand 2-(4-(3-Amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)acetic acid (HY-46618), E3 ligase (2S,4R)-4-Hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (HY-W998248), and PROTAC linker (S)-2-Amino-3,3-dimethylbutanoic acid (HY-59140), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC (HY-125845)[1]. |
| Target | SMARCA2/4 |
| Formula | C38H47N9O5S |
| Molar Mass | 741.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
PROTAC SMARCA2/4-degrader-26
CAS: F: C38H47N9O5S W: 741.90
PROTAC SMARCA2/4-degrader-26 is a PROTAC targeting SMARCA2/4. PROTAC SMARCA2/4-degrader-25 is composed of PROTAC target
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