Bioactivity | PROTAC SMARCA2/4-degrader-25 is a PROTAC targeting SMARCA2/4. PROTAC SMARCA2/4-degrader-25 is composed of E3 ligase (2S,4R)-4-Hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (HY-W998248), PROTAC Linker (S)-2-Amino-3,3-dimethylbutanoic acid (HY-59140), and target protein ligand SMARCA2/4-ligand-3 (HY-162814), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC (HY-125845)[1]. |
Target | SMARCA2/4 |
Formula | C44H50N10O9S2 |
Molar Mass | 927.06 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |