PeptideDB

PROTAC SMARCA2/4-degrader-16

CAS: 2568273-64-1 F: C49H59N11O5S W: 914.13

PROTAC SMARCA2/4-degrader-16 (compound I-337) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity PROTAC SMARCA2/4-degrader-16 (compound I-337) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC50s 90 after 24 h of treatment[1].
Target SMARCA2/4
CAS 2568273-64-1
Formula C49H59N11O5S
Molar Mass 914.13
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. World Intellectual Property Organization, WO2020251971 A1 2020-12-17.