| Bioactivity | PROTAC SMARCA2 degrader-4 (Compound I-424) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2. PROTAC SMARCA2 degrader-9 degrades SMARCA2 in MV411 and in A549 with DC50 1 μM[1]. (Pink: Ligand for target protein (HY-159531); Black: Linker (HY-159532); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845)) |
| CAS | 2568523-70-4 |
| Formula | C55H68N12O5S |
| Molar Mass | 1009.27 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ji N, et al., Smarca degraders and uses thereof. US20230072658A1. |
PROTAC SMARCA2 degrader-4
CAS: 2568523-70-4 F: C55H68N12O5S W: 1009.27
PROTAC SMARCA2 degrader-4 (Compound I-424) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2. PR
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