| Bioactivity | PROTAC SMARCA2-degrader-36 (compound 38) is a SMARCA2 degrader and can reach the the degradation rate of 99 % at the 100 nM in H929 cells. PROTAC SMARCA2-degrader-36 shows anti-proliferative activity and can be used for study of cancer(Srtucture Note: PINK SMARCA2 ligand HY-44012; Blue, VHL ligand (HY-112078); Black, linker HY-W014125)[1]. |
| CAS | 2380274-45-1 |
| Formula | C48H65N9O6S |
| Molar Mass | 896.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sanjita SASMAL, et al. Pyridazine derivatives as smarca2/4 degraders. WO2019207538 A1. 2024-03-19. |
PROTAC SMARCA2 degrader-31
CAS: 2380274-45-1 F: C48H65N9O6S W: 896.15
PROTAC SMARCA2-degrader-36 (compound 38) is a SMARCA2 degrader and can reach the the degradation rate of 99 % at the 100
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.