Bioactivity | PROTAC SMARCA2 degrader-28 (Compound 158) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 with a DC50 of 3 nM in HiBiT A549 cells. (Pink: Ligand for target protein (HY-168237); Black: Linker (HY-168238); Blue: Ligand for E3 ligase (HY-W087383))[1] |
CAS | 2641510-88-3 |
Formula | C50H51F7N10O10 |
Molar Mass | 1084.99 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Duplessis M, et al., Bifunctional compounds for the treatment of cancer. WO2021083949. |