PeptideDB

PROTAC SMARCA2 degrader-28

CAS: 2641510-88-3 F: C50H51F7N10O10 W: 1084.99

PROTAC SMARCA2 degrader-28 (Compound 158) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 with a DC50 of 3 nM in
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity PROTAC SMARCA2 degrader-28 (Compound 158) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 with a DC50 of 3 nM in HiBiT A549 cells. (Pink: Ligand for target protein (HY-168237); Black: Linker (HY-168238); Blue: Ligand for E3 ligase (HY-W087383))[1]
CAS 2641510-88-3
Formula C50H51F7N10O10
Molar Mass 1084.99
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Duplessis M, et al., Bifunctional compounds for the treatment of cancer. WO2021083949.