| Bioactivity | PROTAC SMARCA2 degrader-26 (compound 45) is a potent SMARCA2 PROTAC degrader. PROTAC SMARCA2 degrader-26 induces SMARCA2 and SMARCA4 degradation in VCaP cells with the percent degradation of 94% and 57% for SMARCA2 and SMARCA4, respectively. PROTAC SMARCA2 degrader-26 shows antiproliferative activity[1]. |
| CAS | 2760247-27-4 |
| Formula | C46H54N8O5S |
| Molar Mass | 831.04 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chandrasekhar ABBINENI, et al. 6-substituted pyridazine compounds as smarca2 and/or smarca4 degraders. WO2022029617A1. |
PROTAC SMARCA2 degrader-26
CAS: 2760247-27-4 F: C46H54N8O5S W: 831.04
PROTAC SMARCA2 degrader-26 (compound 45) is a potent SMARCA2 PROTAC degrader. PROTAC SMARCA2 degrader-26 induces SMARCA2
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