| Bioactivity | PROTAC SMARCA2 degrader-21 (Compound I-5) is a PROTAC degrader for SMARCA, that degrades SMARCA2 with a DC50 of 10-50 nM in A549 cell, and degrades SMARCA2 and SMARCA4 in MV411 with DC50 of 100 nM, respectively[1]. |
| CAS | 2891464-61-0 |
| Formula | C54H66N12O5S |
| Molar Mass | 995.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang Y, et al., Smarca degraders and uses thereof. WO2023278402. |
PROTAC SMARCA2 degrader-21
CAS: 2891464-61-0 F: C54H66N12O5S W: 995.24
PROTAC SMARCA2 degrader-21 (Compound I-5) is a PROTAC degrader for SMARCA, that degrades SMARCA2 with a DC50 of 10-50 nM
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