| Bioactivity | PROTAC SMARCA2 degrader-1 (compound ex7) is a BRM2 (SMARCA2) degrader (DC50<0.1 μM). PROTAC SMARCA2 degrader-1 is also an E3 ubiquitin ligase binding linker useful in research of cancers. PROTAC SMARCA2 degrader-1 is a target protein ligand-linker conjugate[1]. |
| Target | BRM2 (SMARCA2) |
| Name | PROTAC SMARCA2 degrader-1 |
| CAS | 2892523-73-6 |
| Formula | C49H62N10O6S |
| Molar Mass | 919.14 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lu Liang, et al. Preparation of pyridazine derivatives as BRM targeting compounds and E3 ubiquitin ligase binding agents for the treatment of cancers. World Intellectual Property Organization, WO2023287787 A1 2023-01-19. |