Bioactivity | PROTAC PIN1 degrader-1 is a targeted PROTAC for PIN1. PROTAC PIN1 degrader-1 can degrade the PIN1 protein in MDA-MB-468 triple-negative breast cancer cells, with a DC50 value of 0.018 μM. PROTAC PIN1 degrader-1 can be used for tumor research[1]. |
Target | PIN1 |
CAS | 3038591-59-9 |
Formula | C51H52N10O7 |
Molar Mass | 917.02 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liu C, et al. Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs. J Med Chem. 2024 Sep 12;67(17):15780-15795. |