PeptideDB

PROTAC KRAS G12D degrader 1

CAS: F: C59H72F2N10O7S W: 1103.33

PROTAC KRAS G12D degrader 1 is a potent, rapid, and selective degrader of protac KRASG12D with DC50 of 38.06 nM. PROTAC
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity PROTAC KRAS G12D degrader 1 is a potent, rapid, and selective degrader of protac KRASG12D with DC50 of 38.06 nM. PROTAC KRAS G12D degrader 1 showes significant antitumor efficacy[1].
Name PROTAC KRAS G12D degrader 1
Formula C59H72F2N10O7S
Molar Mass 1103.33
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Zhou C, et al. Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D. J Med Chem. 2024 Jan 10.