Bioactivity | PROTAC KRAS G12D degrader 1 is a potent, rapid, and selective degrader of protac KRASG12D with DC50 of 38.06 nM. PROTAC KRAS G12D degrader 1 showes significant antitumor efficacy[1]. |
Name | PROTAC KRAS G12D degrader 1 |
Formula | C59H72F2N10O7S |
Molar Mass | 1103.33 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Zhou C, et al. Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D. J Med Chem. 2024 Jan 10. |