| Bioactivity | pan-KRAS degrader 5 (compound 102) is a potent cereblon-based KRAS PROTAC degrader, with a DC50 of <100 nM. pan-KRAS degrader 5 shows anticancer effects. (Pink: ligand for target protein (HY-168679); Black: linker (HY-168670); Blue: E3 ligase ligand (HY-W580113))[1]. |
| CAS | 3052745-46-4 |
| Formula | C57H65F2N11O5 |
| Molar Mass | 1022.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jesus Raul Medina. Cereblon-based kras degrading protacs and uses related thereto. US20240287101A1. |