| Bioactivity | PROTAC K-Ras Degrader-3 (compound 40) is a PROTAC degrader of K-Ras with a DC50 of ≤ 1 nM against SW620 KRAS G12D, and a GI50 of ≤ 10 nM against SW620 3D cell growth. PROTAC K-Ras Degrader-3 can be utilized in cancer research[1]. |
| CAS | 3043670-68-1 |
| Formula | C57H67F2N9O6 |
| Molar Mass | 1012.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Robert L, et al. Glutarimide-containing pan-kras-mutant degrader compounds and uses thereof, WO2024118966A1, 2024-06-06 |
PROTAC K-Ras Degrader-3
CAS: 3043670-68-1 F: C57H67F2N9O6 W: 1012.20
PROTAC K-Ras Degrader-3 (compound 40) is a PROTAC degrader of K-Ras with a DC50 of ≤ 1 nM against SW620 KRAS G12D, and
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