| Bioactivity | PROTAC JNK1-targeted-1 (PA2) is a JNK1 PROTAC degrader, with a DC50 of 10 nM. PROTAC JNK1-targeted-1 (PA2) decreases the level of Fibronectin protein. PROTAC JNK1-targeted-1 can be used for the research of pulmonary fibrosis[1]. (Pink: JNK1 inhibitor (HY-170602); Black: linker (HY-40178); Blue: CRBN Ligand (HY-41547)) |
| Formula | C35H32BrN9O6 |
| Molar Mass | 754.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Guo Y, et al. Design and synthesis of JNK1-targeted PROTACs and research on the activity. Bioorg Chem. 2025 Jan;154:108044. |
PROTAC JNK1-targeted-1
CAS: F: C35H32BrN9O6 W: 754.59
PROTAC JNK1-targeted-1 (PA2) is a JNK1 PROTAC degrader, with a DC50 of 10 nM. PROTAC JNK1-targeted-1 (PA2) decreases the
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