Bioactivity | PROTAC IRAK3 degrade-1 formic is a potent and selective degrader of IRAK3 (IC50=5 nM)[1]. |
Target | IRAK3 |
Name | PROTAC IRAK3 degrade-1 formic |
Formula | C48H65N11O8 |
Molar Mass | 924.10 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Degorce SL, et al. Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase. J Med Chem. 2020 Sep 24;63(18):10460-10473. |