| Bioactivity | PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 μM in HT1080 cells[1]. |
| Invitro | PROTAC GPX4 degrader-1 (DC-2) has been found to induce GPX4 degradation and subsequent ferroptosis[1]. Western Blot Analysis[1]. Cell Line: |
| Name | PROTAC GPX4 degrader-1 |
| CAS | 2916433-81-1 |
| Formula | C50H57ClN10O10 |
| Molar Mass | 993.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Han Wang, et al. Discovery of ML210-Based glutathione peroxidase 4 (GPX4) degrader inducing ferroptosis of human cancer cells. Eur J Med Chem. 2023 Jun 5;254:115343. |
PROTAC GPX4 degrader-1
CAS: 2916433-81-1 F: C50H57ClN10O10 W: 993.50
PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 μM in HT1080 cells.
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This product is for research use only, not for human use. We do not sell to patients.