| Bioactivity | PROTAC ER Degrader-11 (Example 26-1) is a potent PROTAC ER degrader, with the IC50 of 0.66 nM. PROTAC ER Degrader-11 plays an important role in cancer research(Sturcture Note:(Blue: Cereblon ligand (HY-W797329), Black: linker (HY-W262798)；Pink: ER ligand (HY-196271))[1]. |
| CAS | 2846112-04-5 |
| Formula | C43H53N5O4 |
| Molar Mass | 703.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jiangsu Hengrui Pharmaceuticals Co., Ltd, et al. Tetrahydronaphthalene compound, and preparation method therefor and use thereof in medicine. World Intellectual Property Organization, WO2022206737 A1 2022-10-06 |
PROTAC ER Degrader-11
CAS: 2846112-04-5 F: C43H53N5O4 W: 703.91
PROTAC ER Degrader-11 (Example 26-1) is a potent PROTAC ER degrader, with the IC50 of 0.66 nM. PROTAC ER Degrader-11 pla
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