| Bioactivity | PROTAC CDK9 degrader-7 is a PROTAC targeting to CDK9 sepcifically. PROTAC CDK9 degrader-7 mediates CDK9 degradation via the proteasome[1]. |
| Invitro | PROTAC CDK9 degrader-7 (compound 15f) 降解 CDK9，在 Molm-13 细胞中显示出最大的效力，IC50 为 40 nM [1]。 Western Blot Analysis[1] Cell Line: |
| Name | PROTAC CDK9 degrader-7 |
| Formula | C43H50Cl2N8O9 |
| Molar Mass | 893.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tokarski RJ 2nd, et al. Bifunctional degraders of cyclin dependent kinase 9 (CDK9): Probing the relationship between linker length, properties, and selective protein degradation. Eur J Med Chem. 2023 Jun 5;254:115342. |
PROTAC CDK9 degrader-7
CAS: F: C43H50Cl2N8O9 W: 893.81
PROTAC CDK9 degrader-7 is a PROTAC targeting to CDK9 sepcifically. PROTAC CDK9 degrader-7 mediates CDK9 degradation via
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