PROTAC BTK Degrader-2_product_DataBase

CAS: 2250382-66-0 F: C47H54F2N8O13 W: 976.97

PROTAC BTK Degrader-2 is a potent BTK PROTAC degrader. PROTAC BTK Degrader-2 effectively reduces BTK protein levels.

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	PROTAC BTK Degrader-2 is a potent BTK PROTAC degrader. PROTAC BTK Degrader-2 effectively reduces BTK protein levels[1].
Invitro	PROTAC BTK Degrader-2 (compound 10; 1 µM; 24 h; Ramos 细胞) 促进培养细胞中的 BTK 降解[1]。
In Vivo	PROTAC BTK Degrader-2 (compound 10; 0-175 mg/kg; s.c.) 在大鼠体内选择性降解 BTK[1]。 Animal Model:
Name	PROTAC BTK Degrader-2
CAS	2250382-66-0
Formula	C47H54F2N8O13
Molar Mass	976.97
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Zorba A, et, al. Delineating the role of cooperativity in the design of potent PROTACs for BTK. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):E7285-E7292.

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