Bioactivity | PROTAC BTK Degrader-11 is a PROTAC degrader that can break down BTK, with a DC50 of 1.7 nM. PROTAC BTK Degrader-11 can be used in cancer research. (Pink: target protein ligand (HY-159956); Black: linker; Blue: E3 ligase (HY-150839))[1]. |
CAS | 2736508-94-2 |
Formula | C48H55N11O4 |
Molar Mass | 850.02 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Haitao Wang, et al. BGB-16673, A BTK Degrader, Overcomes On-Target Resistance From BTK Inhibitors And Present. FRANKFURT VIRTUAL. 2023. P1219. |