Bioactivity | PROTAC BRD4 Degrader-9 (compound 8a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively[1]. | |||||||||
Name | PROTAC BRD4 Degrader-9 | |||||||||
CAS | 2417370-42-2 | |||||||||
Formula | C59H71F2N9O15S4 | |||||||||
Molar Mass | 1312.50 | |||||||||
Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
Storage |
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