PeptideDB

PROTAC BRD4 Degrader-9

CAS: 2417370-42-2 F: C59H71F2N9O15S4 W: 1312.50

PROTAC BRD4 Degrader-9 (compound 8a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrad
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity PROTAC BRD4 Degrader-9 (compound 8a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively[1].
Name PROTAC BRD4 Degrader-9
CAS 2417370-42-2
Formula C59H71F2N9O15S4
Molar Mass 1312.50
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month