Bioactivity | PROTAC BRD4 Degrader-27 is a PROTAC that selectively targets BRD4 (rather than BRD2/BRD3). PROTAC BRD4 Degrader-27 consists of E3 ubiquitinase ligand Thalidomide-4-OH (HY-103596), PROTAC Linker γ-Aminobutyric acid (HY-N0067) and PROTAC target protein ligand PROTAC BRD4 ligand-3 (HY-162876), of which the active control of the target protein ligand is Mivebresib (HY-100015), and the conjugate of E3 ubiquitin ligase ligand + Linker is Pomalidomide 4'-alkylC3-acid (HY-131875)[1]. |
Target | BRD4 |
CAS | 2407163-44-2 |
Formula | C37H30F2N6O7 |
Molar Mass | 708.67 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |