| Bioactivity | PROTAC BRD4 Degrader-10 (compound 8b) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 1.3 nM and 18 nM, respectively[1]. |
| Name | PROTAC BRD4 Degrader-10 |
| CAS | 2417370-49-9 |
| Formula | C59H71F2N9O15S4 |
| Molar Mass | 1312.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
PROTAC BRD4 Degrader-10
CAS: 2417370-49-9 F: C59H71F2N9O15S4 W: 1312.50
PROTAC BRD4 Degrader-10 (compound 8b) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degra
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This product is for research use only, not for human use. We do not sell to patients.