| Bioactivity | PROTAC AR Degrader-5 (compound A46) is a potent AR PROTAC Degrader with an IC50 value of 49 nM. PROTAC AR Degrader-5 inhibits sebaceous plaque and induces hair regeneration[1]. |
| In Vivo | PROTAC AR Degrader-5 (compound A46) (100, 200, 400, 800 µg + 12 µg TP; Skin application; daily for 21 days) 抑制金仓鼠的皮脂斑[1]。PROTAC AR Degrader-5 (5, 10, 30 mg/ml +DHT 30 mpk; 150 µL; Skin application; 2 times a day for 17 days) 诱导 C57BL/6N 小鼠毛发再生[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 2703021-51-4 |
| Formula | C52H54F4N8O7S2 |
| Molar Mass | 1043.16 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. YouZhi Tong, et al. Bifunctional compound, preparation method therefor, and use thereof. WO2021180160A1. |
PROTAC AR Degrader-5
CAS: 2703021-51-4 F: C52H54F4N8O7S2 W: 1043.16
PROTAC AR Degrader-5 (compound A46) is a potent AR PROTAC Degrader with an IC50 value of 49 nM. PROTAC AR Degrader-5 inh
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.