Bioactivity | PROTAC ACC degrader-1 (Compound 9b) is a Acetyl-CoA Carboxylase degrader. PROTAC ACC degrader-1 exhibits superior potency against Aphis craccivora (IC50 = 107.8 μg/mL). (Srtucture Note: Pink, Target protein ligand (HY-169009); Blue, E3 ligand (HY-163440); Black, linker (HY-W007559)[1]. |
Formula | C37H42N4O8 |
Molar Mass | 670.75 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Xu Q, et al. Acetyl-CoA Carboxylase Proteolysis-Targeting Chimeras: Conceptual Design and Application as Insecticides. J Agric Food Chem. 2024 Aug 28;72(34):18809-18815. |