| Bioactivity | PRMT6-IN-2 (compound 2) is a dual inhibitor of protein arginine methyltransferase PRMT6 and CARM1 with an IC50 of 30 nM. PRMT6 is abnormally expressed in many cancer cells, and PRMT6-IN-2-based derivatives have potential anticancer activity. |
| CAS | 912970-79-7 |
| Formula | C23H28FN3O |
| Molar Mass | 381.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor |
PRMT6-IN-2
CAS: 912970-79-7 F: C23H28FN3O W: 381.49
PRMT6-IN-2 (compound 2) is a dual inhibitor of protein arginine methyltransferase PRMT6 and CARM1 with an IC50 of 30 nM.
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