| Bioactivity | PRMT5-IN-46 (compound 278) inhibits PRMT5 with IC50 of 1-10 μM. PRMT5 is a methyltransferase which is associated with specific genetic alterations. PRMT5-IN-46 can be used to treat proliferative diseases, metabolic disorders, and blood diseases.[1] |
| CAS | 380192-76-7 |
| Formula | C19H22ClNO2 |
| Molar Mass | 331.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. DUNCAN, et al. PRMT5 inhibitors and uses thereof. WO2014100695. World Intellectual Property Organization. 2014-06-26. |