| Bioactivity | PRMT5-IN-25 (compound 503) is a potent PRMT5 inhibitor with an Ki value of 0.06 nM. PRMT5-IN-25 shows antiproliferative[1]. | ||||||||||||
| Invitro | PRMT5-IN-25 (6 days) 对HCT116-MTAP null、HCT116-WT细胞显示出抗增殖活性，IC50 值分别为0.026、0.068μM[1]。 | ||||||||||||
| Name | PRMT5-IN-25 | ||||||||||||
| CAS | 2691869-82-4 | ||||||||||||
| Formula | C24H21F3N6O | ||||||||||||
| Molar Mass | 466.46 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Jennifer Rebecca Allen, et al. Novel prmt5 inhibitors. WO2021163344A1. |
PRMT5-IN-25
CAS: 2691869-82-4 F: C24H21F3N6O W: 466.46
PRMT5-IN-25 (compound 503) is a potent PRMT5 inhibitor with an Ki value of 0.06 nM. PRMT5-IN-25 shows antiproliferative.
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