| Bioactivity | PRMT4-IN-2 (compound 55) is a pan-inhibitor of protein arginine methyltransferase (PRMT) with IC50s of 92 nM (PRMT4), 436 nM (PRMT6), 460 nM (PRMT1), 823 nM ( PRMT8), 1.386 μM (PRMT3)[1]. |
| Target | IC50: 92 nM (PRMT4), 436 nM (PRMT6), 460 nM (PRMT1), 823 nM (PRMT8), 1.386 μM (PRMT3) |
| Name | PRMT4-IN-2 |
| Formula | C23H29N7O |
| Molar Mass | 419.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bhattacharya D, et al. Development of selective class I protein arginine methyltransferase inhibitors through fragment-based drug design approach. Eur J Med Chem. 2023 Nov 15;260:115713.. |