Bioactivity | PRE-084 (hydrochloride) (Standard) is the analytical standard of PRE-084 (hydrochloride). This product is intended for research and analytical applications. PRE-084 hydrochloride is a highly selective σ1 receptor (S1R) agonist, with an IC50 of 44 nM. PRE-084 hydrochloride exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 hydrochloride also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway. |
CAS | 75136-54-8 |
Formula | C₁₉H₂₈ClNO₃ |
Molar Mass | 353.88 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |