| Bioactivity | PPAR agonist 5 (compound 4b) is a potent PPAR agonist with EC50 values of 3.20, 1.51, 1.92 µM for PPARα, PPARβ/δ, PPARγ, respectively. PPAR agonist 5 shows anti-inflammatory effect[1]. |
| Invitro | PPAR agonist 5 (compound 4b) (10 µM; 4, 24 h) 降低 LPS (HY-D1056) 诱导的 CCL-2 和 IL-6 mRNA 的表达[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PPAR agonist 5 相关抗体: RT-PCR[1] Cell Line: |
| Formula | C26H29NO3 |
| Molar Mass | 403.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Villarroel-Vicente C, et al. Synthesis of a new 2-prenylated quinoline as potential drug for metabolic syndrome with pan-PPAR activity and anti-inflammatory effects. Bioorg Med Chem Lett. 2024 Jul 1;106:129770. |