PeptideDB

PPACK

CAS: 71142-71-7 F: C21H31ClN6O3 W: 450.96

PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminoge
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Bioactivity PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1].
Name PPACK
CAS 71142-71-7
Sequence {d-Phe}-Pro-{Arg-Chloromethylketone}
Shortening {d-Phe}-P-{Arg-Chloromethylketone}
Formula C21H31ClN6O3
Molar Mass 450.96
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Mohler MA, et, al. D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thromb Haemost. 1986 Oct 21;56(2):160-4.