Bioactivity | PPACK is a plasminogen activator (rt-PA) inhibitor. PPACK can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK also inhibits the binding of rt-PA to plasma protease inhibitors[1]. |
Name | PPACK |
CAS | 71142-71-7 |
Sequence | {d-Phe}-Pro-{Arg-Chloromethylketone} |
Shortening | {d-Phe}-P-{Arg-Chloromethylketone} |
Formula | C21H31ClN6O3 |
Molar Mass | 450.96 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mohler MA, et, al. D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thromb Haemost. 1986 Oct 21;56(2):160-4. |