Bioactivity | PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer[1]. |
Name | PP5-IN-1 |
CAS | 1022417-69-1 |
Formula | C18H18N2O3S |
Molar Mass | 342.41 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Elham F Ahanin, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chem Biol. 2023 Oct 19;30(10):1223-1234.e12. |