| Bioactivity | POSH-IN-2 (MIDI), a mitochondrial division inhibitor, is a DRP1 inhibitor that potently blocks mitochondrial fragmentation induced by cellular stresses and genetic mitochondrial lesions. MIDI covalently interacts with DRP1-C367 to target DRP1 interaction with multiple receptors[1]. |
| CAS | 348145-43-7 |
| Formula | C22H16N2O2 |
| Molar Mass | 340.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jun Yang, et al. Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction. Cell Chem Biol. 2023 Mar 16;30(3):278-294.e11. |
POSH-IN-2
CAS: 348145-43-7 F: C22H16N2O2 W: 340.37
POSH-IN-2 (MIDI), a mitochondrial division inhibitor, is a DRP1 inhibitor that potently blocks mitochondrial fragmentati
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