| Bioactivity | PMT-O9-1A is a potent PD-L1 degrader. PMT-O9-1A decreases the protein expression of PD-L1. PMT-O9-1A shows cytotoxicity. PMT-O9-1A shows anticancer activity[1]. |
| Invitro | PMT-O9-1A 与去泛素化酶 CSN5 相互作用并抑制其功能，导致 PD-L1 泛素化降解[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> PMT-O9-1A 相关抗体: |
| Formula | C22H25ClN2O4 |
| Molar Mass | 416.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zeng Z, et al. Advancing Cancer Immunotherapy through Engineering New PD-L1 Degraders: A Comprehensive Study from Small Molecules to PD-L1-Specific Peptide-Drug Conjugates. J Med Chem. 2024 Oct 18. |