| Bioactivity | PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation levels. PM-81I can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer[1]. |
| Target | STAT6. |
| Invitro | PM-81I (0.05, 0.1, 0.5, 1, 2.5, 5 µM; 2 h) inhibits IL-4 stimulated phosphorylation of STAT6 in Bease-2B immortalized human epithelial airway cells[1]. Western Blot Analysis[1] Cell Line: |
| Name | PM-81I |
| CAS | 1637532-83-2 |
| Formula | C43H58F2N3O10P |
| Molar Mass | 845.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. John S, et al. Stat6 inhibitors. Patent WO2014182928A2. |
PM-81I
CAS: 1637532-83-2 F: C43H58F2N3O10P W: 845.91
PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation
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